The first season follows the rescue of Lincoln Burrows, who is accused of murdering Terrence Steadman, the brother of the Vice President of the United States. Lincoln is sentenced to death and is incarcerated in Fox River State Penitentiary where he awaits his execution.
Lincoln's brother, brilliant structural engineer Michael Scofield, is convinced of Lincoln's innocence and formulates an escape plan. In order to gain access to Fox River, Michael commits an armed robbery which results in his being sentenced to Fox River.
In prison, Michael befriends the prison doctor Sara Tancredi when he pretends to suffer from Type 1 diabetes, in order to gain daily access to the prison's infirmary. The brothers' fight to ward off the execution is aided by their lifelong friend Veronica Donovan, who begins to investigate the conspiracy that put Lincoln in jail. However, they are hindered by covert agents, members of an organization known as The Company. The Company was responsible for framing Lincoln, and they did so because of Lincoln's father, Aldo Burrows, and his former connections to the company.
The brothers, along with six other inmates, Fernando Sucre, Theodore "T-Bag" Bagwell, Benjamin Miles "C-Note" Franklin, David "Tweener" Apolskis, John Abruzzi, and Charles "Haywire" Patoshik, who come to be known as the Fox River Eight, escape in the season finale.
That's a big tattoo plan!!
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